Wednesday 18 March 2020

Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy



Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy


Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal 'firing' in the central nervous system and for brain and heart function. These channels use a ''ball-and-chain'' mechanism to help regulate their ion flow, according to a new study.

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